基本信息

姓名：董臣

性别：男

学历：博士

职称：副教授

招生方向：1、萜类物质合成的分子机制解析及关键酶的理性设计；2、食品加工与安全

联系方式：chen.dong@haut.edu.cn

个人简介

主要对植物萜类代谢途径中的关键分支酶进行研究，分析萜类物质合成的调控机制；通过理性设计对萜类物质合成关键酶进行改造，实现植物酶的人工智能设计，调控整个萜类物质合成的代谢流。主持完成国家自然科学基金项目1项，河南省自然科学基金面上项目2项，河南省科技攻关项目1项，以及河南省教育厅项目1项。以第一作者或者通讯作者在Science Bulletin、Journal of Agricultural and Food Chemistry、International Journal of Biological Macromolecules、Journal of the Science of Food and Agriculture等发表SCI论文20余篇，参与申报发明专利17项。

代表性论文：

1. Dong C^#., Qu G^#., Guo JG^#., Wei F., Gao SW., Sun ZT., Jin LF., Sun XW., Rochaix JD., Miao YC^*., Wang R^*. Rational Design of Geranylgeranyl Diphosphate Synthase Enhances Carotenoid Production and Improves Photosynthetic Efficiency in Nicotiana tabacum. Science Bulletin. 2022; 67:315-327.

2. Wang ZW., Shen YP., Cao LY., Li H., Li HF., Song LJ., Ma XT., Dong C^*. Enhancing the Catalytic Activity of Geranylgeranyl Diphosphate Synthase through Ancestral Sequence Reconstruction and Semirational Design. Journal of Agricultural and Food Chemistry. 2024; 72(34):19187-19196

3. Xin Y., Liu ZZ., Yang CH., Dong C^*., Chen FS^*., Liu KL^*. Smart antimicrobial system based on enzyme-responsive high methoxyl pectin-whey protein isolate nanocomplex for fresh-cut apple preservation. International Journal of Biological Macromolecules. 2023; 253:127064

4. Zhang C^#., Xin Y^#., Wang ZW., Qin LL., Cao LY., Li HF., Ma XT., Yin JY., Zhao ZX., Liu PJ., Tang JW., Dong C^*. Melatonin-induced myeloblastosis viral oncogene homologs alleviate fresh-cut lotus root browning during storage by attenuating flavonoid biosynthesis and reactive oxygen species. Journal of the Science of Food and Agriculture. 2023; 103 (11):5452-5461.

5. Qin LL., Du F., Yang NN., Zhang C., Wang ZW., Zheng XW., Tang JW., Yang LB., Dong C*. Transcriptome Analyses Revealed the Key Metabolic Genes and Transcription Factors Involved in Terpenoid Biosynthesis in Sacred Lotus. Molecules. 2022; 27:4599.